Precision Diagnosis & Prognosis Enabled by Mechanism-Driven Protein Conformational Biomarkers Case Studies
Time: 12:00 pm
day: Day Two Track A AM
Details:
- Protein confirmational changes commonly precede onset of human diseases
- Detection and quantification of nonnative protein structures using proteomics of disease-driving protein may serve as diagnostic and prognostic biomarker
- Importance of establishing biomarker correlation with clinical outcome
- Case studies of Transthyretin Amyloidosis and Systemic Amyloidosis
