New Paradigm in Liquid Biopsy: In Vivo Early Diagnosis of Multiple Diseases by Detection of Circulating Markers Directly in the Patient’s Bloodstream with Cytophone
Time: 12:30 pm
day: Day One Track A AM
Details:
- Defining a new strategy for early cancer diagnosis with photoacoustic detection of rare circulating tumor cells (CTCs) in a large blood volume (up to 1 L) with no blood draw.
- Clinical validation of 1000-fold sensitivity improvement down to 1 CTC/L by precise detection of CTCs in patients with stage I-II melanoma.
- Identification of single and clustered CTCs, cancer-induced clots, and CTC–clot emboli.
- Theranostics platform for real-time monitoring of personalized laser-mediated anti-CTC and anticoagulant therapy efficiency to reduce the risk of metastasis and stroke.
- Approaches for expanding to screening, minimal residual disease, recurrence, multiple cancers, infection complications, and cardiovascular disorders (e.g., thrombosis and pulmonary embolism).
- Solving challenges in standardization, marker variability, motion, and skin pigmentation.
