Roundtable Discussion: Designing Clinical Trials with MRD as a Patient Identification Tool to Transform Precision Oncology

  • What are the biggest opportunities and limitations of leveraging MRD as a patient identification tool compared with its use for monitoring or as a trial endpoint?
  • How are pharma and biotech teams approaching assay selection given variability in MRD sensitivity and methodologies?
  • What practical challenges – regulatory, operational, or clinical – remain for embedding MRD-driven patient identification into trial design at scale?